Verdict
Built from the measurements below
- Accuracy is too close to call: Mistral Medium 3.5 scored 28.8% and Mistral Small 4 32.5% on the same 80 questions, a gap within what chance alone could produce.
- Mistral Small 4 is 13× cheaper per question as billed ($0.0019 vs $0.025), reasoning tokens included.
- Mistral Small 4 generates text 1.2× faster: 170 tokens per second against 145.
Which should you choose?
Choose Mistral Small 4 for the lower cost per correct answer ($0.0057 against $0.087), faster streaming and open weights you can run yourself. The widest subject gap is in medicine: Mistral Small 4 answered 5 of 11 correctly, Mistral Medium 3.5 3 of 11. With so few questions per subject, treat this as a lead to test on your own prompts, not a result.
Accuracy gap -3.8 points (z = -0.51). We call a winner only when z is at least 1.96, the usual 95% threshold. Speed, latency and price need a 10% margin.